Osteoinduction by demineralised bone
نویسندگان
چکیده
منابع مشابه
Augmentation and repair of tendons using demineralised cortical bone
BACKGROUND In severe injuries with loss of tendon substance a tendon graft or a synthetic substitute is usually used to restore functional length. This is usually associated with donor site morbidity, host tissue reactions and lack of remodelling of the synthetic substitutes, which may result in suboptimal outcome. A biocompatible graft with mechanical and structural properties that replicate t...
متن کاملBiomaterial osteoinduction
search between a Dutch group and a group in Chengdu, China,4,5 revealed that similar bone formation was seen with porous ceramics of various types of hydroxyapatite, tricalcium phosphate, and Bioglass® (NovaBone Products, Alachua, FL, USA). Fujibayashi and others in our department6 also reported that porous titanium processed with alkali-heat treatment has osteoinduction. This material contains...
متن کاملOsteoinduction using bone morphogenic protein in irradiated tissue.
OBJECTIVE To prove the efficacy of bone morphogenic protein as an osteoinductive agent in irradiated tissue. DESIGN Prospective randomized controlled trial designed to test the effectiveness of recombinant bone morphogenic protein 2 (rBMP-2) combined with solid hydroxyapatite disks in an irradiated tissue bed. SUBJECTS Eighteen adult, male, white New Zealand rabbits weighing 3.0 to 3.5 kg. ...
متن کاملEnhanced Osteoinduction by Biodegradable Gelatin-β-tricalcium Phosphate Sponge Capable for Bone Morphogenetic Protein Release
The objective of this study is to develop an osteoinductive scaffold which enables the controlled release of bone morphogenetic protein (BMP)-2. A biodegradable gelatin sponge incorporating 50 wt% of btricalcium phosphate (β-TCP) was fabricated to investigate the osteoinduction activity. The sponge prepared had an interconnected pore structure with an average pore size of 200 mm. The in vivo re...
متن کاملEnhanced activity of demineralised bone matrix augmented with xenogeneic bone morphogenetic protein complex in rats.
INTRODUCTION Demineralised bone matrix (DBM) is an allograft material widely used as a bone filler and bone graft substitute. DBM contains bone morphogenetic proteins (BMPs), which induce and regulate bone formation during embryogenesis and in postnatal life. AIMS AND OBJECTIVES To investigate the osteoinductivity of DBM augmented with xenogeneic BMP-complex at different doses. MATERIALS AN...
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ژورنال
عنوان ژورنال: International Orthopaedics
سال: 1998
ISSN: 0341-2695,1432-5195
DOI: 10.1007/s002640050273